WebFeb 15, 2010 · The cTnTR141W transgenic mice aged 2 months were divided into model group and TMPP group, whereas age-matched … WebCardioprotection by Hepc1 in cTnTR141W transgenic mice Author: Li Zhang, Dan Lu, Wei Zhang, Xiongzhi Quan, Wei Dong, Yanfeng Xu, Lianfeng Zhang Source: Transgenic …

Human umbilical cord blood derived mesenchymal stem cells …

WebThe transgenic mice were created by the method of microinjection. And they were del crossed with cTnTR141W transgenic mice. The cardiac structure and function were analysed with M-mode echocardiography. Survival data of the experimental mice were recorded. Pathologic changes were observed by light microscopy. WebMSCs significantly decreased chamber dilation and contractile dysfunction in cTnT R141W mouse. MSCs transplanted hearts showed a significant decrease in cardiac apoptosis and their regulation with Akt pathway. Cardiac fibrosis and cytoplasmic vacuolization in the MSCs group was significantly lower. boot stretcher

The changes of the cardiac structure and function in …

WebThe α-myosin heavy chain cTnTR141W transgenic mouse was previously reported as a model for dilated cardiomyopathy (DCM), and it was used to test the effects of combinations of Rb1 and TMPP in reversing the progression of DCM and the potential mechanism. WebJan 1, 2016 · Hearts in the DCM and DCM + PBS groups were grossly enlarged and heavier than those from the control group.After MSC treatment, the cardiac sizes decreased (Fig. 2A).The HW/BW ratio was increased by 30% in the DCM group (p < 0.01) and reduced by 10% in the DCM + MSC group (p < 0.05).Cardiomyocyte hypertrophy is indicated by … WebNov 1, 2015 · Download Citation Human umbilical cord blood derived mesenchymal stem cells improve cardiac function in cTnTR141W transgenic mouse of dilated cardiomyopathy Cell transplantation is a promising ... boot stretcher for wide feet