Ctps1 antibody
WebCTPS1 protein expression summary - The Human Protein Atlas. CTPS1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTPS1 INFORMATION. Proteini. Full gene name according to HGNC. CTP synthase 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. WebAntibody was affinity purified using an epitope specific to CTPS1 immobilized on solid support. The epitope recognized by A304-543A maps to a region between residue 541 to …
Ctps1 antibody
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WebAnti-CPS1 antibody (ab3682) Datasheet SDS Reviews ( 9) Q&A (3) References (21) Key features and details Rabbit polyclonal to CPS1 Suitable for: IHC-Fr, IHC-P, IP, ICC/IF, … WebMar 19, 2013 · Only 1/10 RR positive sera had detectable antibodies to IMPHD2 and none had antibodies to CTPS1. Potentially important autoantibody targets identified on protein arrays included Myc-associated zinc finger protein (MAZI) and ankyrin repeat motif. The majority of HCV patients with RR autoantibodies previously received IFN/ribavirin …
WebCTPS1 is an enzyme involved in the CTP biosynthesis pathway and catalyzes the conversion of UTP to CTP. Arrows signify steps in the pathway. Green arrows signify activation of pyrimidine and purine biosynthesis pathways by ATP and GTP. Red angled line signifies inhibition of the pyrimidine biosynthesis pathway by end product CTP. WebMar 12, 2024 · Using a newly available anti-CTPS1 monoclonal antibody, which gives a more sensitive and specific signal than the polyclonal antibody previously used ( …
WebMay 28, 2014 · CTPS1 expression was found to be low in resting T cells, but rapidly upregulated following TCR activation. These results highlight a key and specific role of … Webfor independent verification of CTPS1 gene silencing results, individual siRNA duplex components are also available upon request. suitable control antibody: CTPS1 Antibody (2G7-1D10): sc-293266. sqRT-PCR Primer also available: CTPS1 (h)-PR: sc-78858-PR, 20 µl. Get details about si/shRNA Gene Silencers. See Protocol Online.
WebDetails of Functionality. This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
WebThe intact gene sequence encoding the human CTP synthase 1 (CTPS1) is expressed in the yeast. The resulting protein is fused with the 6xHis-tag to generate the recombinant human CTPS1 protein. Its purity reaches up to 90% measured by SDS-PAGE. On the gel, this recombinant CTPS1 protein migrated to the molecular weight band of about 70 kDa. how big was the louisiana purchase territoryWebCTPS1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC . Full gene name according to HGNC . how many oz in one third cupWebDec 15, 2024 · CTPS forms the cytoophidium in various human cancers. (A-F) The signal of anti-CTPS1 antibody on representative cytoophidium-high sections. (G and H) Immunofluorescence with anti-CTPS1 antibody on tissue sections of non-cancerous prostate and colon. Scale bars = 50 µm. (A′-H′) Magnified images of selected areas … how many oz in pound in foodWebThis enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L … how big was the louisiana purchase in acresWebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent … how big was the mauryan armyWebAntibodies and Immunoblotting —Anti-CTPS1 (human) antibody was generated by Rockland Immunochemicals using a carboxyl-terminal peptide (amino acids 578–591, H 2 N-CSEITELKFPSINHD-COOH) containing an amino-terminal cysteine for coupling to peptide affinity column and keyhole limpet hemocyanin. how big was the marlin in old man and the seaWebSep 30, 2024 · Selective inhibition of CTPS1 is a promising approach for the treatment of autoimmune and other T cell-driven diseases, but little is known about the mechanisms underlying selective versus non-selective inhibition. Nimbus scientists, in partnership with researchers from the University of Washington and Schrödinger, used cryo-electron ... how many oz in one shot