Web6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate. Targets&IC50 WebApr 30, 2002 · Hence, 5PAH is the best inhibitor of the isomerization reaction reported to date with a K(i) of 2 x 10(-7) M. Here we report the crystal structure of rabbit phosphoglucose isomerase complexed with ...
The inhibition of phosphoglucose isomerase by - ScienceDirect
WebThe phosphomannose-isomerase is encoded by the manA gene from Escherichia coli and catalyzes the conversion of mannose-6-phosphate to fructose-6-phosphate, an … WebFeb 15, 1993 · Abstract Abstract With 13C NMR, phosphoglucose isomerase (PGI; D-glucose-6-phosphate ketol-isomerase, EC 5.3.1.9) is shown to produce mannose 6-phosphate (M6P) slowly from a much more rapidly catalyzed equilibrium between glucose 6-phosphate (G6P) and fructose 6-phosphate (F6P). sims 4 follow sim to work mod
The use of the phosphomannose-isomerase/mannose …
Webphosphoglucose isomerase Inhibitors The Biocompare Inhibitor Search Tool lets researchers browse thousands of compounds by searching by inhibitor name or by its target enzyme. Simply search by “Keywords” if you know the name of the inhibitor, or search by “Inhibitor Target” to enter the name of your protein of interest. WebThe inhibition of phosphoglucose isomerase by erythrose 4-phosphate is competitive with both of the substrates for this enzyme (Figs. 1-2). With fructose 6-phosphate as substrate several experiments were carried out (Fig. 1), from which Km for fructose 6-phosphate was calculated to be 8 x 10-5 M. Ki for erythrose 4-phosphate was found to lie ... WebReaction. alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate. Synonyms. 6-Phosphoglucose isomerase, AfcPGI, AMF, AMF/PGI, At4g24620, autocrine motility ... sims 4 folder path